You can destroy depression.
You don't have to get on with it, learn to live with it or have it on and off for years (rest of your life even).
What you describe as depression is something that looks like a state, that seems to be infleuncing you in certain way.. It is in fact aftereffect of beliefs - you could say negative beliefs - that you are trying to get something by having, but they are not serving the purpose.
They key is to see what you are trying to get here. It may me multiple beliefs also.
The beliefs needs to see the truth - when they see they are not true, they dissolve. They let go of themselves. They disappear and you can't even remember how they look like and how they influenced you. Sometimes you don't even remember what the belief was.. That's how amazingly it let's go
I had depression since I can remember untill I saw through it. At one point I said to myself that I have to figure this out, that I can't go with it anymore. I sat down on my chair and figure it out.. I saw the reason and it dissolved itself. From that moment on, I didn't feel like that before solving it. It is hard to remember how it was even (thank god). It doesn't influence me anymore. Simply because it is not there..
It was something about getting approval and not wanting to do anything or something. I can't remember it.
It feels like something moving from your body sometimes, or pressures getting relaxed, I felt liek a stone was being moved out of my stomach and flying out of my body, etc. Emotional knots untying.
These beleifs can be always boiled down to simple, one sentence statements. Not buts, no maybe.. Thinks like "I'm not going to get food with this"
"I can't have a girl comparable with other guys' girls"
etc
There are many methods as how to do this. I can't speak for all people, but just trying to do you best at your career and life goals won't help these... It is an inner work, but it impacts your outside life. A lot. And it is worth it.. Oh god how it is worth it.
Some people prefer to just feel into the emotions and feel them through, some people here do some kind of their own logical looking into these things, I use this investigative trying to figure out what is there and what I'm trying to get etc, there is also Release technique, EFT..
I'd suggest joining
http://www.ballsproject.com which many people here are members of - They focus on dealing with these emotional things there, how it realtes to work, sex, all kinds of things
It some of this resonates with you, good.. If it doesn't that's also good.. Maybe something else will